Allergic Reactions to Environmental Types

Intended Use:

The test is used for the diagnosis of sensitizations that may lead to allergy-associated symptoms such as conjunctivitis, rhinitis or gastro-intestinal problems. The test is designed for semiquantitative in vitro determination of allergen specific IgE (sIgE) in plasma, contributing to the diagnosis of allergies.

The measurement range is given in EAST system classes 0 to 6.

Acceptable Sample Types:

Serum and Dried-Blood Spot (DBS)

Clinical Significance:

The term allergy means an oversensitivity to foreign substances which are normally harmless. Alongside any genetic predisposition, numerous non-genetic factors also play a role, such as exposure to the allergen, nutritional condition, existing chronic diseases and acute viral infections. Atopy is a hereditary disposition to developing allergic reactions such as allergic asthma, rhinitis (hay fever) or dermatitis (including atopic eczema)

More than 15% of the population in industrial countries suffer from an immediate-type allergy. Typical allergic reactions are rhinitis, conjunctivitis and allergic asthma. A worldwide increase in allergic rhinitis has been observed, with a prevalence of 4% to more than 40% in various regions. Inhalation allergies can be triggered by seasonal allergens (pollen from trees, grasses and weeds) or all-year-round indoor allergens (house dust mites, domestic animals, mould spores). The allergic symptoms intensify with every further exposure to the allergen. If a systemic allergic reaction occurs, serious, even life- threatening reactions can result (anaphylactic shock).







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